{"id":43020,"date":"2024-11-14T15:06:33","date_gmt":"2024-11-14T15:06:33","guid":{"rendered":"https:\/\/www.theisn.org\/?page_id=43020"},"modified":"2026-10-21T19:04:24","modified_gmt":"2026-10-21T19:04:24","slug":"ckm-roadmap","status":"publish","type":"page","link":"https:\/\/www.theisn.org\/initiatives\/toolkits\/ckm-roadmap\/","title":{"rendered":"Cardio-Kidney-Metabolic Initiative"},"content":{"rendered":"<p>[vc_row][vc_column][vc_column_text]<\/p>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p>Kidney diseases are intricately linked to increased morbidity with, and mortality from, other diseases and infections. An integrated approach to noncommunicable disease (NCD) prevention and management that recognizes the burden of kidney disease and concomitant co-morbidities is critical to ensure no disease is left behind.<\/p>\n<p>Since 2022, the ISN has led a cardio-kidney-metabolic initiative, bringing together nephrologists and cardiologists to identify existing gaps related to targets for therapy, optimal management, and barriers to implementation. The aim is to fill these gaps by developing toolkits to support clinicians and advance care for individuals living with cardio-kidney-metabolic conditions and complications.<\/p>\n<\/div>\n<\/div>\n<p>[\/vc_column_text][vc_column_text]<\/p>\n<div class=\"wpb_text_column wpb_content_element \">\n<div class=\"wpb_wrapper\">\n<p><strong>Roadmap to Persons Living with Cardio-Kidney-Metabolic Conditions<\/strong><\/p>\n<p style=\"font-weight: 400\">To guide our work, we have developed <a href=\"https:\/\/www.theisn.org\/initiatives\/toolkits\/ckm_roadmap\/\" target=\"_blank\" rel=\"noopener\">an interactive roadmap<\/a>, which provides clinicians with an overview of the management of individuals living with cardio-kidney-metabolic conditions and complications. <strong><a href=\"https:\/\/www.theisn.org\/initiatives\/toolkits\/ckm_roadmap\/\" target=\"_blank\" rel=\"noopener\">Visit the roadmap here.<\/a><\/strong><\/p>\n<\/div>\n<p><a href=\"https:\/\/www.theisn.org\/initiatives\/toolkits\/ckm_roadmap\/\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-43067\" src=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2024\/11\/CKM-Roadmap-300x168.png\" alt=\"\" width=\"500\" height=\"280\" srcset=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2024\/11\/CKM-Roadmap-400x224.png 400w, https:\/\/www.theisn.org\/wp-content\/uploads\/2024\/11\/CKM-Roadmap-367x205.png 367w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><\/p>\n<\/div>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space height=&#8221;16px&#8221;][vc_text_separator title=&#8221;Resources&#8221; title_align=&#8221;separator_align_left&#8221; border_width=&#8221;3&#8243;][vc_empty_space height=&#8221;16px&#8221;][vc_tta_accordion spacing=&#8221;5&#8243; gap=&#8221;5&#8243; c_position=&#8221;right&#8221; active_section=&#8221;&#8221; collapsible_all=&#8221;true&#8221; el_class=&#8221;accordion-isn&#8221;][vc_tta_section title=&#8221;Meeting Report &#8211; ISN Cardiovascular-Kidney-Metabolic Health Expert Forum&#8221; tab_id=&#8221;Forum&#8221;][vc_column_text]<\/p>\n<h3><strong>Access the full paper <a href=\"https:\/\/www.kidney-international.org\/article\/S0085-2538(26)00620-4\/fulltext\" target=\"_blank\" rel=\"noopener\">here<\/a>.<\/strong><a href=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/09\/Infographic-ISN_CKM.pdf\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-55204 size-full\" src=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/09\/CKM-Expert-Forum-Image.png\" alt=\"\" width=\"1750\" height=\"982\" \/><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-56489 aligncenter\" src=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/10\/CKM-Forum-Thumbnail-300x170.png\" alt=\"\" width=\"417\" height=\"236\" srcset=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/10\/CKM-Forum-Thumbnail-400x226.png 400w, https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/10\/CKM-Forum-Thumbnail-367x208.png 367w\" sizes=\"(max-width: 417px) 100vw, 417px\" \/><\/a><\/h3>\n<h5 style=\"text-align: center\">Download the infographic <a href=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/10\/Infographic-ISN_CKM.pdf\" target=\"_blank\" rel=\"noopener\">here<\/a>.<\/h5>\n<p>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Optimisation of RAASi Therapy Toolkit&#8221; tab_id=&#8221;RAASi&#8221;][vc_column_text]<\/p>\n<p style=\"font-weight: 400\">The optimization of RAASi therapy and management of related complications was selected as the first implementation activity of the roadmap given the significant unmet need in this area, and the underutilization of RAASi therapy. The toolkit aims to provide\u00a0focused, up-to-date, practical tools, and serve\u00a0as a hands-on reference for nephrologists and cardiologists, as well as other healthcare professionals,\u00a0involved in the multidisciplinary care of patients with cardio-renal complications.<\/p>\n<p style=\"font-weight: 400\">Five\u00a0educational and clinical tools were developed on the following topics:\u00a0nuts-and-bolts of RAASi therapy; management of hyperkalemia; diet; managing acute declines in eGFR; and, patient knowledge.<\/p>\n<p>NEW: A brand new tool on indications for MRAs in the management of cardio-kidney risk has just been added. Access it <a href=\"https:\/\/www.theisn.org\/initiatives\/toolkits\/raasi-toolkit\/#MRAs\" target=\"_blank\" rel=\"noopener\">here<\/a>.<\/p>\n<p style=\"font-weight: 400\"><a href=\"https:\/\/www.theisn.org\/initiatives\/raasi-toolkit\/\" target=\"_blank\" rel=\"noopener noreferrer\">Access the entire optimization of RAASi therapy toolkit here.<\/a><\/p>\n<p>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Optimization of SGLT2i Therapy Toolkit&#8221; tab_id=&#8221;SGLT2i&#8221;][vc_column_text]The toolkit on the optimization of SGLT2i therapy was the next output selected for the cardio-kidney-metabolic initiative.<\/p>\n<p>The toolkit contains focused and practical infographics on:<\/p>\n<ul>\n<li>Nuts and Bolts of SGLT2i Therapy in the Intersection of Kidney and Cardiovascular Disease<\/li>\n<li>Practical Points for SGLT2 Inhibitor Usage<\/li>\n<li>Mitigate Adverse Effects of SGLT2 Inhibitors<\/li>\n<li>SGLT2 Inhibitor Cold Map<\/li>\n<li>Talking to Your Patients About SGLT2 Inhibitor Therapy<\/li>\n<li>Understanding SGLT2 Inhibitor Therapy<\/li>\n<\/ul>\n<p><a href=\"https:\/\/www.theisn.org\/initiatives\/toolkits\/sglt2i-toolkit\/\" target=\"_blank\" rel=\"noopener noreferrer\">Access the optimization of SGLT2i therapy toolkit here.<\/a>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Combination Therapies Toolkit&#8221; tab_id=&#8221;Combination&#8221;][vc_column_text]Coming soon![\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Additional Resources&#8221; tab_id=&#8221;Resources&#8221;][vc_row_inner][vc_column_inner][vc_empty_space height=&#8221;16px&#8221;][vc_text_separator title=&#8221;Resources for Primary Care&#8221; title_align=&#8221;separator_align_left&#8221; border_width=&#8221;2&#8243;][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_column_text]<a href=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/03\/Cardio-Kidney-Metabolic.pdf\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-53083\" src=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/03\/SPP_CKM-300x211.png\" alt=\"\" width=\"277\" height=\"195\" \/><\/a>[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_empty_space height=&#8221;40px&#8221;][vc_column_text]<\/p>\n<p style=\"text-align: center\">Guidance for Primary Care: Supporting Individuals Towards Maintaining Cardio-Kidney-Metabolic Health<\/p>\n<h5 style=\"text-align: center\"><a href=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/09\/Cardio-Kidney-Metabolic_Chinese.pdf\">Chinese<\/a> | <a href=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/03\/Cardio-Kidney-Metabolic.pdf\">English<\/a> | <a href=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/07\/Cardio-Kidney-Metabolic_French.pdf\">French<\/a> | <a href=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/09\/Cardio-Kidney-Metabolic-German.pdf\">German<\/a> | <a href=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/09\/Cardio-Kidney-Metabolic_Japanese.pdf\">Japanese<\/a> | <a href=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/07\/Cardio-Kidney-Metabolic_Spanish.pdf\">Spanish<\/a><\/h5>\n<p>[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/3&#8243;][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner][vc_empty_space height=&#8221;16px&#8221;][vc_text_separator title=&#8221;Other Resources&#8221; title_align=&#8221;separator_align_left&#8221; border_width=&#8221;2&#8243;][vc_empty_space height=&#8221;10px&#8221;][\/vc_column_inner][\/vc_row_inner]<a class=\"porto-sicon-box-link\" href=\"https:\/\/eur05.safelinks.protection.outlook.com\/?url=https%3A%2F%2Fx.com%2FISNkidneycare%2Fstatus%2F2104843703596568703%3Fs%3D20&#038;data=05%7C02%7Cmmoorthy%40Theisn.org%7Caeeb41eaeaa1411e8aed08df1e3a6d62%7C9353336200694ec4b905d4dcc7a8a0ef%7C0%7C0%7C639262908462126284%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&#038;sdata=0Kl6vuCy9hILZN8R1MyXutZIgTZ96SQbhiLi3JMkfkc%3D&#038;reserved=0\" target='_blank'><div class=\"porto-sicon-box style_1 default-icon\"><div class=\"porto-sicon-default\"><div id=\"porto-icon-119135676ae8314a885fa\" class=\"porto-just-icon-wrapper\" style=\"text-align:center;\"><div class=\"porto-icon none\" style=\"color:#66cccc;font-size:32px;display:inline-block;\"><i class=\"fab fa-twitter\"><\/i><\/div><\/div><\/div><div class=\"porto-sicon-header\" ><h4 class=\"porto-sicon-title\" style=\"\">World Heart Day 2026 - Tweetorial<\/h4><\/div> <!-- header --><\/div><!-- porto-sicon-box --><\/a><a class=\"porto-sicon-box-link\" href=\"https:\/\/eur05.safelinks.protection.outlook.com\/?url=https%3A%2F%2Ftheisn.outgrow.us%2FCKM_QUIZ&#038;data=05%7C02%7Cmmoorthy%40Theisn.org%7Caeeb41eaeaa1411e8aed08df1e3a6d62%7C9353336200694ec4b905d4dcc7a8a0ef%7C0%7C0%7C639262908462146107%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&#038;sdata=5D%2FyQj4rSYEKZjYP353LenzuoF81r3jgl%2F8FUm1zF4Y%3D&#038;reserved=0\" target='_blank'><div class=\"porto-sicon-box style_1 default-icon\"><div class=\"porto-sicon-default\"><div id=\"porto-icon-6669385976ae8314a886f2\" class=\"porto-just-icon-wrapper\" style=\"text-align:center;\"><div class=\"porto-icon none\" style=\"color:#66cccc;font-size:32px;display:inline-block;\"><i class=\"far fa-list-alt\"><\/i><\/div><\/div><\/div><div class=\"porto-sicon-header\" ><h4 class=\"porto-sicon-title\" style=\"\">World Heart Day 2026 - Quiz<\/h4><\/div> <!-- header --><\/div><!-- porto-sicon-box --><\/a><a class=\"porto-sicon-box-link\" href=\"https:\/\/eur05.safelinks.protection.outlook.com\/?url=https%3A%2F%2Ftwitter.com%2Fi%2Fspaces%2F1pJdRDLWoaLKW&#038;data=05%7C02%7Cmmoorthy%40Theisn.org%7Caeeb41eaeaa1411e8aed08df1e3a6d62%7C9353336200694ec4b905d4dcc7a8a0ef%7C0%7C0%7C639262908462094322%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&#038;sdata=zFUtLafRF6FoCJSm7H3oSPGdIyYWY5Urave2Kacp8fQ%3D&#038;reserved=0\" target='_blank'><div class=\"porto-sicon-box style_1 default-icon\"><div class=\"porto-sicon-default\"><div id=\"porto-icon-7347581406ae8314a887b9\" class=\"porto-just-icon-wrapper\" style=\"text-align:center;\"><div class=\"porto-icon none\" style=\"color:#66cccc;font-size:32px;display:inline-block;\"><i class=\"fas fa-caret-square-right\"><\/i><\/div><\/div><\/div><div class=\"porto-sicon-header\" ><h4 class=\"porto-sicon-title\" style=\"\">World Heart Day 2026 - X Space<\/h4><\/div> <!-- header --><\/div><!-- porto-sicon-box --><\/a>[vc_empty_space height=&#8221;24px&#8221;][vc_text_separator title=&#8221;World Kidney Day 2027&#8243; title_align=&#8221;separator_align_left&#8221; border_width=&#8221;2&#8243;][vc_empty_space height=&#8221;16px&#8221;][vc_column_text]<a href=\"https:\/\/www.worldkidneyday.org\/2027-campaign\/\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-55520\" src=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/09\/WKD2027-LinkedIn-Banner-1128x19172dpi.png\" alt=\"\" width=\"533\" height=\"90\" srcset=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/09\/WKD2027-LinkedIn-Banner-1128x19172dpi-400x68.png 400w, https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/09\/WKD2027-LinkedIn-Banner-1128x19172dpi-367x62.png 367w\" sizes=\"(max-width: 533px) 100vw, 533px\" \/><\/a>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Support&#8221; tab_id=&#8221;Support&#8221;][vc_column_text]<\/p>\n<h4 style=\"text-align: center\">The Cardio-Kidney-Metabolic Initiative is supported by unrestricted educational grants from<\/h4>\n<p style=\"text-align: center\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-43533\" src=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2024\/12\/ASTRAZENECA-LOGO-300x99.png\" alt=\"\" width=\"200\" height=\"66\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-43536\" src=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2024\/12\/Bayer-logo-300x169.png\" alt=\"\" width=\"107\" height=\"60\" \/><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-53843 alignnone\" src=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2026\/05\/Boehringer_Logo_RGB_Dark-Green.png\" alt=\"\" width=\"175\" height=\"53\" \/>\u00a0 \u00a0 \u00a0\u00a0<img loading=\"lazy\" decoding=\"async\" class=\"wp-image-43544 alignnone\" src=\"https:\/\/www.theisn.org\/wp-content\/uploads\/2024\/12\/Novo_Nordisk_-_Logo.svg-FROM-GOOGLE.png\" alt=\"\" width=\"86\" height=\"63\" \/><\/p>\n<h5><\/h5>\n<h5 style=\"text-align: center\">The Cardio-Kidney-Metabolic Initiative was developed with support from unrestricted educational grants from AstraZeneca and CSL Vifor.<\/h5>\n<p>[\/vc_column_text][\/vc_tta_section][\/vc_tta_accordion][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text] Kidney diseases are intricately linked to increased morbidity with, and mortality from, other diseases and infections. An integrated approach to noncommunicable disease (NCD) prevention and management that recognizes the burden of kidney disease and concomitant co-morbidities is critical to ensure no disease is left behind. Since 2022, the ISN has led a cardio-kidney-metabolic initiative, [&hellip;]<\/p>\n","protected":false},"author":37,"featured_media":0,"parent":37555,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-43020","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.theisn.org\/wp-json\/wp\/v2\/pages\/43020"}],"collection":[{"href":"https:\/\/www.theisn.org\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.theisn.org\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.theisn.org\/wp-json\/wp\/v2\/users\/37"}],"replies":[{"embeddable":true,"href":"https:\/\/www.theisn.org\/wp-json\/wp\/v2\/comments?post=43020"}],"version-history":[{"count":7,"href":"https:\/\/www.theisn.org\/wp-json\/wp\/v2\/pages\/43020\/revisions"}],"predecessor-version":[{"id":56491,"href":"https:\/\/www.theisn.org\/wp-json\/wp\/v2\/pages\/43020\/revisions\/56491"}],"up":[{"embeddable":true,"href":"https:\/\/www.theisn.org\/wp-json\/wp\/v2\/pages\/37555"}],"wp:attachment":[{"href":"https:\/\/www.theisn.org\/wp-json\/wp\/v2\/media?parent=43020"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}