The prevalence of kidney failure in older people is increasing. However, there is insufficient evidence to determine whether dialysis or conservative kidney management (CKM) is better for this population.\u00a0<\/span><\/p>\n Twenty-four non-<\/span>randomised<\/span> studies (26,127 people \u226565 years with kidney failure) were identified. Most studies were at high or unclear risk of bias for most methodological domains. Compared to dialysis, CKM had uncertain effects on death and cardiovascular death. For health-related quality of life, the Physical and Mental Component Summary scores were lower with CKM compared with dialysis.<\/span><\/p>\n <\/p>\n<\/div>\n <\/p>\n Farrington_K, Covic_A, Nistor_I, Aucella_F, Clyne_N, De Vos_L, et al. Clinical practice guideline on management of older patients with chronic kidney disease stage 3b or higher (eGFR < 45 mL\/min\/1.73 m2): a summary document from the European Renal Best Practice Group. Nephrology Dialysis Transplantation<\/a>. 2017;32(1):9\u201316.<\/p>\n<\/li>\n Davison_SN, Pommer_W, Brown_MA, Douglas_CA, Gelfand_SL, Gueco_IP, et al. Conservative kidney management and kidney supportive care: core components of integrated care for people with kidney failure<\/a>. Kidney International. 2024;105(1):35\u201345.<\/p>\n<\/li>\n Murtagh_FE, Burns_A, Moranne_O, Morton_RL, Naicker_S. Supportive care: comprehensive conservative care in end-stage kidney disease<\/a>. Clinical Journal of the American Society of Nephrology. 2016;11(10):1909\u20131914.<\/p>\n<\/li>\n Voorend_CG, van_Oevelen_M, Verberne_WR, van_den_Wittenboer_ID, Dekkers_OM, Dekker_F, et al. Survival of patients who opt for dialysis versus conservative care: a systematic review and meta-analysis. Nephrology Dialysis Transplantation.<\/a> 2022;37(8):1529\u20131544.<\/p>\n<\/li>\n Foote_C, Kotwal_S, Gallagher_M, Cass_A, Brown_M, Jardine_M. Survival outcomes of supportive care versus dialysis therapies for elderly patients with end-stage kidney disease: a systematic review and meta-analysis.<\/a> Nephrology. 2016;21(3):241\u2013253.<\/p>\n<\/li>\n Reindl-Schwaighofer_R, Kainz_A, Kammer_M, Dumfarth_A, Oberbauer_R. Survival analysis of conservative vs. dialysis treatment of elderly patients with CKD stage 5.<\/a> PLoS ONE [Electronic Resource]. 2017;12(7):e0181345.<\/p>\n<\/li>\nLearning objectives:<\/strong><\/h4>\n
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