{"id":54785,"date":"2026-07-16T10:49:52","date_gmt":"2026-07-16T10:49:52","guid":{"rendered":"https:\/\/www.theisn.org\/?post_type=event&#038;p=54785"},"modified":"2026-09-22T11:25:21","modified_gmt":"2026-09-22T11:25:21","slug":"industry-e-symposium-genetic-and-clinical-implications-in-ahus-management","status":"publish","type":"event","link":"https:\/\/www.theisn.org\/blog\/event\/industry-e-symposium-genetic-and-clinical-implications-in-ahus-management\/","title":{"rendered":"Industry e-symposium: Genetic and Clinical Implications in aHUS Management"},"content":{"rendered":"<p>[vc_row][vc_column][vc_column_text]This webinar will explore the critical role of genetics in the prognosis and management of atypical Hemolytic Uremic Syndrome (aHUS), with a focus on practical clinical applications. Key topics include using genetic insights for\u00a0risk stratification, determining\u00a0prognosis, and guiding\u00a0treatment duration and goals. Designed for a global audience, the session will address how clinicians can integrate genetic data into actionable strategies to improve patient outcomes across diverse healthcare settings.<\/p>\n<h4><strong>Learning objectives:\u00a0<\/strong><\/h4>\n<ul>\n<li><strong>Role of Genetics<\/strong>: Understand the critical importance of genetic insights in managing atypical Hemolytic Uremic Syndrome (aHUS) and how it is not necessary for diagnosis but informative for prognosis.<\/li>\n<li><strong>Risk Stratification<\/strong>: Learn how to use genetic data to assess patient risk levels and tailor clinical approaches accordingly.<\/li>\n<li><strong>Prognosis Determination<\/strong>: Gain knowledge on leveraging genetic information to predict disease progression and outcomes for better patient planning.<\/li>\n<li><strong>Practical Integration<\/strong>: Explore actionable strategies to incorporate genetic data into everyday clinical practice across diverse healthcare settings.<\/li>\n<\/ul>\n<h4><strong>Further reading:<\/strong><\/h4>\n<ul>\n<li>Anuja Java aHUS Diagnosis, Management and Discontinuation of Treatment 2024 ASH education program DOI 10.1182\/hematology.2024000543<\/li>\n<li>Ren Z, et al., (2021) Clinicopathologic Implications of Complement Genetic Variants in Kidney Transplantation. Front. Med. 8:775280. doi: 10.3389\/fmed.2021.775280<\/li>\n<li>Le Quintrec et al 2013 Complement Genes Strongly Predict Recurrence and Graft Outcome in Adult Renal Transplant Recipients with Atypical Hemolytic and Uremic Syndrome American Journal of Transplantation 2013; 13: 663\u2013675 doi: 10.1111\/ajt.12077<\/li>\n<li>Klomjit et al., Gene\u2212Environment Interaction: Lessons From Complement-Mediated Kidney Disease Seminars in Nephrology, Vol45, No4, July 2025,151657<\/li>\n<li>Noris M, Bresin E, Mele C, et al. Genetic Atypical Hemolytic-Uremic Syndrome. 2007 Nov 16 [Updated 2021 Sep 23]. In: Adam MP, Feldman J, Mirzaa GM, et al., editors. GeneReviews\u00ae [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2025. Bookshelf URL: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/\">https:\/\/www.ncbi.nlm.nih.gov\/books\/<\/a><\/li>\n<li>Franz Shaefer et al., Clinical and genetic predictors of atypical hemolytic uremic syndrome phenotype and outcome Kidney International (2018) 94, 408\u2013418; https:\/\/doi.org\/10.1016\/ j.kint.2018.02.029<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_row_inner equal_height=&#8221;yes&#8221;][vc_column_inner][vc_column_text css=&#8221;.vc_custom_1784198924009{margin-top: 10px !important;margin-right: 10px !important;margin-bottom: 10px !important;margin-left: 10px !important;padding-top: 20px !important;padding-right: 20px !important;padding-bottom: 20px !important;padding-left: 20px !important;background-color: #ebebeb !important;border-radius: 5px !important;}&#8221; el_class=&#8221;spk&#8221;]<\/p>\n<p style=\"text-align: center\"><strong>Speakers<\/strong><\/p>\n<div class=\"x_x_ms-outlook-mobile-reference-message x_x_skipProofing\" style=\"text-align: center\" role=\"presentation\">\n<p>Anuja Java (USA)<\/p>\n<\/div>\n<div id=\"gtx-trans\" style=\"position: absolute;left: -66px;top: 78.2363px\">\n<div class=\"gtx-trans-icon\"><\/div>\n<\/div>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row content_placement=&#8221;middle&#8221; css=&#8221;.vc_custom_1671727669697{margin-bottom: 25px !important;}&#8221;][vc_column width=&#8221;1\/6&#8243;][\/vc_column][vc_column width=&#8221;1\/6&#8243;][\/vc_column][\/vc_row][vc_row disable_element=&#8221;yes&#8221;][vc_column][vc_column_text]\n\t\t\t<!-- START Academy banner REVOLUTION SLIDER 6.2.6 --><p class=\"rs-p-wp-fix\"><\/p>\n\t\t\t<rs-module-wrap id=\"rev_slider_11_1_wrapper\" data-source=\"gallery\" style=\"background:#ffffff;padding:0;margin:0px auto;margin-top:0;margin-bottom:0;\">\n\t\t\t\t<rs-module id=\"rev_slider_11_1\" style=\"\" data-version=\"6.2.6\">\n\t\t\t\t\t<rs-slides>\n\t\t\t\t\t\t<rs-slide data-key=\"rs-73\" data-title=\"Slide\" 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\n\t\t\t\t\t\t\t\tclass=\"acadamy-title\"\n\t\t\t\t\t\t\t\tdata-type=\"text\"\n\t\t\t\t\t\t\t\tdata-color=\"#ffffff\"\n\t\t\t\t\t\t\t\tdata-rsp_ch=\"on\"\n\t\t\t\t\t\t\t\tdata-xy=\"x:278px;y:15px;\"\n\t\t\t\t\t\t\t\tdata-text=\"w:normal;\"\n\t\t\t\t\t\t\t\tdata-dim=\"w:369px;\"\n\t\t\t\t\t\t\t\tdata-frame_0=\"sX:0.8;sY:0.8;\"\n\t\t\t\t\t\t\t\tdata-frame_1=\"e:power4.out;st:2030;sp:1000;sR:2030;\"\n\t\t\t\t\t\t\t\tdata-frame_999=\"o:0;st:w;sR:5970;\"\n\t\t\t\t\t\t\t\tstyle=\"z-index:11;font-family:Roboto;\"\n\t\t\t\t\t\t\t>Access recordings of previous webinars done in collaboration with IPNA \n\t\t\t\t\t\t\t<\/rs-layer><!--\n\n\t\t\t\t\t\t\t--><a\n\t\t\t\t\t\t\t\tid=\"slider-11-slide-73-layer-4\" \n\t\t\t\t\t\t\t\tclass=\"rs-layer acadamy-banner-button rev-btn\"\n\t\t\t\t\t\t\t\thref=\"https:\/\/academy.theisn.org\/ipna\" target=\"_blank\" rel=\"nofollow 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noopener\"\n\t\t\t\t\t\t\t\tdata-type=\"shape\"\n\t\t\t\t\t\t\t\tdata-rsp_ch=\"on\"\n\t\t\t\t\t\t\t\tdata-xy=\"x:-51px;y:-43px;\"\n\t\t\t\t\t\t\t\tdata-text=\"w:normal;\"\n\t\t\t\t\t\t\t\tdata-dim=\"w:850px;h:214px;\"\n\t\t\t\t\t\t\t\tdata-frame_999=\"o:0;st:w;\"\n\t\t\t\t\t\t\t\tstyle=\"z-index:12;background-color:rgba(0,0,0,0);\"\n\t\t\t\t\t\t\t> \n\t\t\t\t\t\t\t<\/a><!--\n-->\t\t\t\t\t\t<\/rs-slide>\n\t\t\t\t\t<\/rs-slides>\n\t\t\t\t\t<rs-progress class=\"rs-bottom\" style=\"visibility: hidden !important;\"><\/rs-progress>\n\t\t\t\t<\/rs-module>\n\t\t\t\t<script type=\"text\/javascript\">\n\t\t\t\t\tsetREVStartSize({c: 'rev_slider_11_1',rl:[1240,1024,778,480],el:[90],gw:[728],gh:[90],type:'standard',justify:'',layout:'fullwidth',mh:\"0\"});\n\t\t\t\t\tvar\trevapi11,\n\t\t\t\t\t\ttpj;\n\t\t\t\t\tjQuery(function() {\n\t\t\t\t\t\ttpj = jQuery;\n\t\t\t\t\t\trevapi11 = tpj(\"#rev_slider_11_1\")\n\t\t\t\t\t\tif(revapi11==undefined || revapi11.revolution == 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-->\n[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"featured_media":54786,"menu_order":0,"template":"","class_list":["post-54785","event","type-event","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/www.theisn.org\/wp-json\/wp\/v2\/event\/54785"}],"collection":[{"href":"https:\/\/www.theisn.org\/wp-json\/wp\/v2\/event"}],"about":[{"href":"https:\/\/www.theisn.org\/wp-json\/wp\/v2\/types\/event"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.theisn.org\/wp-json\/wp\/v2\/media\/54786"}],"wp:attachment":[{"href":"https:\/\/www.theisn.org\/wp-json\/wp\/v2\/media?parent=54785"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}